Abstract Background Transfusion-dependent thalassaemia (TDT) is a hereditary blood disorder in which blood transfusion is the mainstay treatment to prolong survival and improve quality of life.Patients with this disease require blood transfusion at more than 100 ml/kg annually and iron-chelating therapy (ICT) to prevent iron overload (IOL) complica
Evolutionary theories posit that emotions prime organisms for action.This study examined whether corticospinal excitability (CSE) is modulated by the emotional valence of a to-be-grasped stimulus.CSE was estimated based on the amplitude of motor evoked potentials (MEPs) elicited using transcranial magnetic stimulation (TMS) and recorded on the firs
The Moon-based Earth Radiation budget Detector (MERD) is an instrument designed to measure the Earth-reflected Solar Radiation (ERSR) and the Earth thermal radiation from the Moon as part of future Gelatin mission of China's Chang'e project.The accuracy of its calibration technology directly determines the measurement precision.For tr
Summary: Fibrosis-driven solid organ failure is an enormous burden on global health.Spiny mice (Acomys) are terrestrial mammals that can regenerate severe skin wounds without scars to avoid predation.Whether spiny mice also regenerate internal organ injuries is unknown.Here, we show that despite equivalent acute obstructive or ischemic kidney Axle